sativa varieties with either high Δ 9-tetrahydrocannabinolic acid (THCA) or high cannabidiolic acid (CBDA) contents harvested at different times were studied. With this in mind, the cannabinoid and metabolomic profiles from inflorescences of two C.

Given the multiple applications of cannabis in the medical field, it is therefore critical to characterize it according to its chemical composition (i.e., its metabolome) and not only its botanical traits. varieties have been traditionally characterized by their major cannabinoid profile, it is now well established that other plant metabolites can also have physiological effects, including minor cannabinoids, terpenes, and flavonoids. 4Laboratorio de Experimentación Animal – Área Farmacología, Departamento de Ciencias Farmacéuticas, Facultad de Química, Universidad de la República, Montevideo, Uruguay.3Laboratorio de Biocatálisis y Biotransformaciones, Departamento de Química Orgánica and Departamento de Biociencias, Facultad de Química, Universidad de la República, Montevideo, Uruguay.2Laboratorio de Fisicoquímica Orgánica, Departamento de Química del Litoral, Centro Universitario Regional Litoral Norte, Universidad de la República, Paysandú, Uruguay.1Laboratorio de Farmacognosia y Productos Naturales, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Montevideo, Uruguay.Santiago Fernández 1 Rossina Castro 1 Andrés López-Radcenco 2 Paula Rodriguez 3 Inés Carrera 4 Carlos García-Carnelli 1* Guillermo Moyna 2*

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